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Is Estradiol Enanthate Bioidentical?

Written by Sarah Thompson - February 23, 2023

Estradiol enanthate is a type of hormone replacement treatment that is gaining in popularity. It is an estradiol-based medication, which is generally considered to be a bioidentical hormone. However, there are some important differences between bioidentical and synthetic hormones that should be considered before deciding on a particular treatment plan.

What Does Bioidentical Mean?
Bioidentical hormones, also known as “bio-engineered,” are hormones produced from plant sources (such as soya beans), which are then chemically engineered to match the body’s own naturally occurring hormones. These hormones are structurally identical to the ones produced by humans and therefore act in the same way once inside the body. This means that they can be effectively used for hormone replacement therapy (HRT).

What Is Estradiol Enanthate?
Estradiol enanthate is a form of HRT in which estradiol, a natural human estrogen, is combined with an oil-based carrier (an enanthate ester) allowing it to be injected into fat cells beneath the skin. This creates localized doses of estradiol over a sustained period of time without having to take daily pills or pass through liver metabolism as would normally occur with oral medications.

Is Estradiol Enanthate Bioidentical?
Yes, estradiol enanthate is bioidentical in terms of its chemical structure being identical to human endogenous estrogen. This makes it very effective for HRT as any other administered dosage of estradiol would be expected to bring about similar effects in terms of side-effects and benefits compared with naturally occurring estrogen levels in women who have had their ovaries surgically removed or were born without them.

Potential Benefits Of Using Estradiol Enanthate
Some potential advantages associated with using estradile enanthate include:

  • Reduced risk of blood clotting related issues due to injecting into muscle instead of tissue like oral medications do;
  • Improved effectiveness since the injection delivers consistent amounts directly into adipose cells; and
  • Reduced risk for breast cancer as opposed to other forms of HRT due to not having large increases in serum levels following administration.

Risk Factors To Consider Before Taking Estradiol Enanthate
Any form of HRT carries some risks including those associated with taking synthetic hormones such as ethinylestradilol (EE). While estradiel enemthanate has a much lower risk profile than EE, there may still be some risks associated with taking this form of HRT such as increased risk for stroke (due to increased menses duration) and gallbladder disease (due to fat deposits). Therefore, it is important that anyone considering taking this form of HRT consults with their doctor beforehand and discuss all potential risks prior to beginning treatment.

Hormone Treatment Center : A Leader In The Field Of Bioidentical Hormone Replacement Therapy (BHRT)
At Hormone Treatment Center we understand the critical importance proper diagnosis and optimal management when it comes your hormone health––especially given the intricacies involved when choosing bioidential therapies such as estradial enemthanates! We pride ourselves on providing exceptional care based upon current evidence based research findings every step along your journey towards optimal health! Our team brings decades worth experience working within BHERT space so you can rest assured you'll get state-of-the art surety thereto! Contact us today learn more about how we can help you reach your goals!

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